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| Sivakumar, Thillaiampalam; Kothalawala, Hemal; Weerasooriya, Gayani; Seekkuge Susil Priyantha Silva; Puvanendiran, Sumathy; Munkhjargal, Tserendorj; Igarashi, Ikuo; Yokoyama, Naoaki. |
| Throughout the world, infections with the Babesia and Theileria parasites often result in economically significant clinical disease in cattle. We conducted a longitudinal survey of Babesia and Theileria infections in cattle from the Polonnaruwa (n?=?75; dry zone) and Nuwara Eliya (n?=?161; wet zone) districts of Sri Lanka. DNA from blood samples collected in June, September, and December 2014 and March 2015 was screened for Babesia bovis, Babesia bigemina, Theileria annulata and Theileria orientalis using specific polymerase chain reactions (PCRs). Additionally, serum samples collected from the animals were screened using enzyme-linked immunosorbent assays (ELISAs) to detect B. bovis- and B. bigemina-specific antibodies. All of the animals surveyed in... |
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Palavras-chave: Babesia; Cattle; Longitudinal study; Sri Lanka; Theileria. |
| Ano: 2016 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4567 |
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| Volpato, Julieta; Coelho, Mirelly Medeiros; Weinert, Nádia Cristine; Mattoso, Cláudio Roberto Scabelo; Lunardeli, Bruno; Saito, Mere Erika. |
| A babesiose é uma doença causada pelo protozoário do gênero Babesiasp., transmitida por carrapatos ixodídeos. A infestação acomete animaisdomésticos e silvestres. A Babesia parasita os eritrócitos do hospedeiro,causando hemólise intravascular. A babesiose pode ser diagnosticada porobservação direta do parasita em esfregaço sanguíneo ou por técnicas comoa Reação em Cadeia da Polimerase (PCR). O presente trabalho documenta oaparecimento do parasitismo de Babesia em um tamanduá mirim (Tamanduatetradactyla), macho, filhote, trazido ao Hospital de Clínica Veterinária, CAV/UDESC pela polícia ambiental, em setembro de 2011. O animal apresentava-sesubnutrido, com leve hipoglicemia, porém apresentava-se clinicamentebem. Para melhor avaliação do paciente, foi... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tamanduá mirim; Tamandua tetradactyla; Babesia. |
| Ano: 2014 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/23706 |
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| Gonçalves,Patrícia Macêdo. |
| A babesiose bovina e a anaplasmose (Tristeza Parasitária Bovina) são enfermidades transmitidas pelo carrapato Boophilus microplus e por moscas hematófagas, respectivamente, ocorrendo em caráter endêmico no Brasil, acarretando elevadas perdas econômicas na pecuária. Nesse país, observa-se uma grande variedade de fatores epidemiológicos influenciando sua ocorrência, tais como: variação climática, práticas de manejo, controle de carrapato e introdução de bovinos susceptíveis. Assim, esta revisão aborda aspectos epidemiológicos do controle da anaplasmose e da babesiose bovina do Brasil, com ênfase na região sudeste. Fatores que influenciam a instabilidade e a estabilidade enzoótica de ambas as espécies também são discutidos. As medidas de controle empregadas... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anaplasma; Babesia; Epidemiologia; Controle; Brasil. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782000000100030 |
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| Tuvshintulga, B.; Sivakumar, T.; Salama, A.A.; Yokoyama, N.; Igarashi, I; 五十嵐, 郁男; 横山, 直明. |
| Methylene blue, the first fully synthetic drug, has been widely used in medical treatments. A few decades ago, this drug was used as an antimalarial agent. In this study, the in vitro inhibitory effect of methylene blue on Babesia bovis, B. bigemina, B. caballi, and Theileria equi (B. equi) and the in vivo inhibitory effect on B. microti were evaluated. Methylene blue significantly inhibited the growth of B. bovis, B. caballi, and T. equi at a 0.1 μM concentration, while B. bigemina was significantly inhibited at 0.01 μM, on day 3 of cultivation. The half maximal inhibitory concentrations (IC50) of methylene blue against B. bovis, B. bigemina, B. caballi, and T. equi were calculated as 0.83±0.02, 0.68±0.09, 0.54±0.14, and 0.49±0.06 μM, respectively. The... |
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Palavras-chave: Methylene blue; Babesia; Theileria; In vitro; In vivo. |
| Ano: 2015 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4242 |
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| Tuvshintulga, B.; Sivakumar, T.; Yokoyama, N.; Igarashi, I.. |
| Dipyridamole, an antiplatelet drug used for the secondary prevention and treatment of stroke, also has antiplasmodial activity and enhances the activity of chloroquine. We evaluated the inhibitory effects of dipyridamole on the growths of Babesia and Theileria parasites. The growth of B. bovis and T. equi was significantly inhibited at a 25 μM concentration of dipyridamole, while B. bigemina and B. caballi were significantly inhibited at 50 μM and 1 μM concentrations of dipyridamole, respectively, on day 3 of cultivation. The half maximal inhibitory concentration (IC50) of dipyridamole was calculated at 39.5±4.5, 26.3±10.9, 13.2±3.6, and 23.5±0.5 μM on the growth of B. bovis, B. bigemina, B. caballi, and T. equi, respectively. In a viability assay, B.... |
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Palavras-chave: Dipyridamole; Babesia; Theileria; In vitro; In vivo. |
| Ano: 2016 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4497 |
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| Gavião Prado, Luan; Vieira Sene, Rafael; Camargo de Medeiros, Elisângela; Maioli do Nascimento, Letícia; Beatriz França de Faria, Ana. |
| Hemoparasitosis, diseases that may cause clinical and hematological complications, are considered a great challenge to practitioners and clinical pathologists. Its high incidence in all Brazilian territory and the difficulty for a precise diagnosis can lead in most cases to a therapeutic diagnosis. Anaplasma platys, Babesia canis vogeli, Ehrlichia canis, Mycoplasma haemocanis and with a lower frequency and clinical relevance, Anaplasma phagocytophilum are the main etiological agents affecting dogs in Brazil. The climatic conditions found in several Brazilian areas, such as high rain and temperature levels, favor the arthropods vectors life cycles. This subject became an important challenge to both veterinarians and pet owners. These etiological agents... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hemoparasite; Anaplasma; Babesia; Mycoplasma; Ehrlichia; Hemoparasitose; Anaplasma; Babesia; Mycoplasma; Ehrlichia. |
| Ano: 2019 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/37999 |
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| Bork, Sabine; Yokoyama, Naoaki; Okamura, Masashi; Igarashi, Ikuo; 横山, 直明; 五十嵐, 郁男. |
| Recently，we reported the in vitro growth inhibitory effects of the imidazole derivatives，clotrimazole(CLT) and ketoconazole (KC)，and the herbicide，clodinafop-propargyl(CP)，against bovine and equine Babesia parasites. Additionally，in the bovine species，several combined applications of the CLT，KC，and CP were reported to significantly increase the inhibitory effects. In this study，similar combination tests were carried out in order to confirm possible synergistic effects in the equine species，Babesia caballi and Babesia equi. Combinations of CLT/KC， CLT/CP，and CLT/KC/CP exerted a significantly enhanced growth inhibitory efficacy in B. caballi，in contrast to B. equi，where no synergistic effects were observed in any of the combinations. Our results suggest that... |
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Palavras-chave: In vitro; Babesia; Clotrimazole; Ketoconazole; Clodinafop-propargyl. |
| Ano: 2003 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/637 |
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